ANCAassociated vasculitis in a man with scleroderma and pulmonary fibrosis

Main Article Content

Alyson Wong
Christine McDonald
John Thenganatt



Systemic sclerosis, or scleroderma, is a connective tissue disease that causes fibrosis of the skin and potentially internal organs (1). The most common lung findings in those with scleroderma are interstitial lung disease and pulmonary hypertension (1). Here we describe a 58-year-old man with scleroderma, interstitial lung disease and pulmonary arterial hypertension. He presented with atypical pulmonary manifestations and an acute kidney injury caused by a new diagnosis of ANCA-associated vasculitis. 

Abstract 243 | pdf Downloads 134 HTML Downloads 20


1 Strollo D, Goldin J. "Imaging Lung Disease in Systemic Sclerosis." Curr Rheumatol Rep 2010;12:156-161.
2 Kaldas A, Warraich I, Prabhakar S. ANCA associated glomerulonephritis- an in-depth review. J Nephrol Ther 2013;4:147-159.
3 Derrett-Smith EC, Nihtyanova SI, Harvey J, Salama AD, Denton CP. Revisiting ANCA-associated vasculitis in systemic sclerosis: clinical, serological and immunogenetic factors. Rheumatology 2013;52(10):1824-31.
4 Chung MP, Yi CA, Lee HY, Han J, Lee KS. Imaging of Pulmonary Vasculitis. Radiology 2010;255(2):322-41.
5 Herbst T, Van Deerlin VM, Miller WT. The CT Appearance of Lower Respiratory Infection Due to Parainfluenza Virus in Adults. Am J Roentgenol. American Roentgen Ray Society 2013;201(3):550–4.
6 Ferguson PE, Sorrell TC, Bradstock KF, Carr P, Gilroy NM. Parainfluenza Virus Type 3 Pneumonia in Bone Marrow Transplant Recipients: Multiple Small Nodules in High-Resolution Lung Computed Tomography Scans Provide a Radiological Clue to Diagnosis. Clin Infect Dis 2009;48(7):905–9.
7 Berden A, Goceroglu A, Jayne D, et al. "Diagnosis and management of ANCA associated vasculitis." BMJ 2012;344: e26.