Anti-Obesity Medications: An Update for Canadian Physicians

Main Article Content

Renuca Modi
Rameez Kabani
Jerry Dang
Sarah Chapelsky
Arya Sharma


To review for Canadian physicians the latest pharmacological options for obesity management.

Quality of Evidence
A literature search was conducted in PubMed with no time restriction. Canadian and international guidelines referenced. National and international statistics databases quoted for epidemiological data. Levels of evidence range from I to III.

Main Message
As a chronic progressive disease affecting over 7.2 million Canadians, obesity requires early identification and treatment by primary care practitioners. Three anti-obesity medications are approved for use in Canada under the tradenames Xenical®, Saxenda®, and Contrave® which help bridge the gap between non-pharmacological and surgical options for the treatment of obesity. Family physicians are front-line members of the obesity management team and should remain updated on the pharmacological options for weight management.

Anti-obesity medications lead to greater average weight loss when combined with behavior modifications and provide individuals with excess weight a sustainable option for obesity management.

Examiner, à l’intention des médecins canadiens, les dernières options pharmacologiques pour la gestion de l’obésité.

Qualité des preuves
Une recherche documentaire a été effectuée dans PubMed sans restriction de temps. Les lignes directrices canadiennes et internationales sont référencées. Bases de données statistiques nationales et internationales citées pour les données épidémiologiques. Les niveaux de preuve vont de I à III.

Message principal

En tant que maladie chronique progressive touchant plus de 7,2 millions de Canadiens, l’obésité nécessite un dépistage et un traitement précoces par les praticiens de soins primaires. Trois médicaments contre l’obésité sont approuvés au Canada sous les noms commerciaux Xenical®, Saxenda® et Contrave®, qui aident à combler le fossé entre les options non pharmacologiques et chirurgicales pour le traitement de l’obésité. Les médecins de famille sont des membres de première ligne de l’équipe de gestion de l’obésité et doivent se tenir au courant des options pharmacologiques pour la gestion du poids.

Les médicaments contre l’obésité entraînent une perte de poids moyenne plus importante lorsqu’ils sont associés à des modifications du comportement et offrent aux personnes en surpoids une option durable pour la gestion de l’obésité.

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