Tips on Amniotic Fluid Embolism

Main Article Content

Kayvan Aflaki
Sena Aflaki
Joel G. Ray

Amniotic fluid embolism

Abstract

Amniotic fluid embolism (AFE) is a catastrophic, sudden-onset event that must be recognized immediately. Despite the rarity of this condition, both maternal and perinatal morbidity and mortality are significant with AFE, even in cases ideally managed. In this article, we present five key statements covering the risk factors, clinical presentation, and management of AFE in a clinical setting. The purpose of these tips is to provide clinicians with information that may improve their ability to make a timely diagnosis and establish appropriate supportive treatment to patients suffering from AFE.


Résumé
L’embolie amniotique est un événement catastrophique d’apparition soudaine qui doit être détecté immédiatement. Malgré la rareté de cette affection, la morbidité et la mortalité maternelles et périnatales sont importantes, même dans les cas où le traitement est idéal. Dans cet article, nous présentons cinq énoncés clés qui portent sur les facteurs de risque, le tableau clinique et la prise en charge de l’embolie amniotique dans un contexte clinique. Ces astuces visent à fournir aux cliniciens de l’information qui pourrait améliorer leur capacité à poser un diagnostic en temps opportun et à assurer un traitement de soutien approprié aux patientes atteintes d’une embolie amniotique.

Abstract 177 | pdf Downloads 108 HTML Downloads 104

References

1. Knight M, Berg C, Brocklehurst P, et al. Amniotic fluid embolism incidence, risk factors and outcomes: A review and recommendations. BMC Pregnancy Childbirth. 2012;12. http://dx.doi.org/10.1186/1471-2393-12-7
2. Flitzpatrick KE, van den Akker T, Bloemenkamp KWM, et al. Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study. PLoS Med. 2019;16:1–24. http://dx.doi.org/10.1371/journal.pmed.1002962
3. Stanten RD, Iverson LI, Daugharty TM, et al. Amniotic fluid embolism causing catastrophic pulmonary vasoconstriction: Diagnosis by transesophageal echocardiogram and treatment by cardiopulmonary bypass. Obstet Gynecol. 2003;102:496-8. http://dx.doi.org/10.1097/00006250-200309000-00013
4. Pacheco LD, Clark SL, Klassen M, et al. Amniotic fluid embolism: Principles of early clinical management. Am J Obstet Gyneco. 2020;222:48–52. http:// dx.doi.org/10.1016/j.ajog.2019.07.036
5. Viau-Lapointe J, Filewood N. Extracorporeal therapies for amniotic fluid embolism. Obstet Gynecol. 2019;134:989–94. http://dx.doi.org/10.1097/ AOG.0000000000003513