Maternal Metastatic Synovial Sarcoma in Pregnancy

Main Article Content

Maureen Okonkwo
Alison Wallace
Bruce Colwell
Kyle McCoy
Nabha Shetty
Ashley Miller
Christopher M Nash

Keywords

sarcoma, synovial, neoplasm, pregnancy, surgery

Abstract

Pregnancy with known metastatic cancer is rare. A case of a woman with known metastatic synovial sarcoma in pregnancy is presented in the study. Her disease progressed with an enlarging and new pulmonary metastasis requiring bilateral pulmonary metastasectomies, both during pregnancy and after delivery. Her pregnancy was uncomplicated otherwise, and she had a successful at term vaginal delivery of a healthy female baby. During her second pregnancy, her disease aggressively recurred at eight weeks gestation without therapeutic options. Thus, palliative care was initiated and she died shortly thereafter. The implications of sarcoma growth and the potential thromboembolic risk with active malignancy in pregnancy is discussed in the study.



Résumé
La grossesse accompagnée d’un cancer métastatique connu est rare. Cette étude présente le cas d’une femme enceinte atteinte d’un sarcome synovial métastatique connu. Sa maladie a progressé sous forme d’une nouvelle métastase pulmonaire en croissance nécessitant une métastasectomie pulmonaire bilatérale pratiquée pendant la grossesse et après l’accouchement. Sa grossesse s’est déroulée sans autre complication et elle a accouché à terme par voie vaginale d’une fille en bonne santé. Au cours de sa deuxième grossesse, son cancer a récidivé de manière agressive à huit semaines de grossesse sans qu’aucune option thérapeutique ne soit possible. Par conséquent, des soins palliatifs ont été mis en place et elle est décédée peu de temps après. Cette étude exam-ine les conséquences de la croissance du sarcome et le risque thromboembolique potentiel lié aux tumeurs malignes actives durant la grossesse.

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